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An animated, cited guide for students and patients. Educational only, not medical advice. Your place is saved on this device.

Not medical adviceGout Companion is an educational synthesis of published literature for study and patient understanding. It does not replace a clinician. Doses and guideline statements are reported as published, not as instructions for any individual.

Part 1 · The disease

What gout is

Gout is a long-term disease of urate crystal deposits that shows itself as sudden, very painful flares, most often in the big toe. 84,85,105 High urate comes first, crystals form silently, flares follow, and years later some people develop tophi. Below: how common it is, the four stages, and where it strikes.

How common is gout?

The figures below do not measure the same thing. A survey asks people whether a doctor ever told them they have gout. Health records count recorded diagnoses. A model (the Global Burden of Disease study) adjusts many sources to one definition and to a standard age structure. Each bar names its measure. Compare bars of the same kind. 41,80,146

Show

Solid bars: observed (survey or records). Outlined bars: modelled, age-standardised. Grey: not a population sample. Tap a bar for the source and what it counts.

The four stages

Dalbeth and Stamp proposed four stages in 2014. Not everyone moves through all of them, and lowering urate can stop the march at any point. Press play to watch one joint go from stage A to stage D. 77,85

Person

Schematic, not to scale. The person's urate level, the symptom track and the timing are illustrative. Stage boundaries vary from person to person, and stages B and C can last for years.

Where flares strike

Tap a site. Only the big toe has a sourced first-flare percentage; for the other joints the research gives where gout goes, not how often it starts there. 105,337,403

Gout is crystals in joints, not just high uric acid. Where the urate comes from is in Where urate comes from; how it turns into crystals is in Crystals vs serum urate.

Key numbers

Gout Companion is an educational synthesis of the published literature on gout, made for health-science study and for patient understanding.

It is not medical advice. It cannot diagnose, and nothing here should change a treatment without your own clinician. Guideline doses are quoted as published. Please check the original sources, which are listed in full in the Sources module.

Part of Medical Companions, animated and cited guides to one disease each. Also there: FMF Companion, whose colchicine and inflammasome modules this guide builds on, and Alzheimer's Companion.