Not medical advice Gout Companion is an educational synthesis of published literature for study and patient understanding. It does not replace a clinician. Doses and guideline statements are reported as published, not as instructions for any individual.
Gout: an animated, cited guide
This page needs JavaScript for its animations. The outline and key answers are below, and every claim in the full version carries a numbered citation.
Not medical advice. Gout Companion is an educational synthesis of published literature. It does not replace a clinician.
What is in it
What gout is Who gets it, the numbers, and the four stages from high urate to tophi.
Where urate comes from Purines, xanthine oxidase, and how the kidney and gut handle urate.
Crystals vs serum urate Why crystals form above about 6.8 mg/dL and dissolve below the target.
A flare, hour by hour From a shed crystal to the NLRP3 inflammasome, interleukin-1β and neutrophils, then resolution.
Colchicine inside the cell From the pill to the neutrophil to the microtubule.
Treating a flare Colchicine, NSAIDs, glucocorticoids, IL-1 blockers and ice.
Colchicine dosing and safety Published doses, kidney function and drug interactions.
How urate-lowering drugs work Allopurinol, febuxostat, uricosurics and pegloticase.
Treat to target Titrating to below 6 mg/dL, and why flares rise in the first months.
Safety of urate-lowering drugs HLA-B*58:01, the CARES and FAST trials, interactions.
Diagnosis and the ACR/EULAR score Crystals under polarised light, imaging, and the 2015 classification calculator.
The differential Calcium pyrophosphate crystal arthritis, septic arthritis, cellulitis and others.
Gout, kidneys and heart Chronic kidney disease, stones, blood pressure and cardiovascular risk.
Living with gout Diet, alcohol, weight, other medicines and a flare plan.
Nursing care Assessment, giving the medicines, teaching and documentation.
Toward a cure Dissolving crystals for good, and the research pipeline.
History and people From podagra to polarised light and allopurinol.
Flashcards, quiz and glossary Revision for students.
Sources Every reference behind the app.
Part 6 · Context & review
Flashcards & mnemonics
Gout flashcards: urate, crystals, flare treatment, urate-lowering drugs, diagnosis and history, with short exact answers. Tap the card (or press Space) to flip it. Arrow keys move through the deck. Filter by part, or shuffle.
← Previous Flip Next → Shuffle
Mnemonics