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An animated, cited guide for students, people with Parkinson's and caregivers. Educational only, not medical advice. Your place is saved on this device.

Not medical adviceParkinson's Companion is an educational synthesis of published literature for study, patient understanding and family caregivers. It does not replace a clinician. Doses and guideline statements are reported as published, not as instructions for any individual, and Parkinson's medicines should never be stopped suddenly.

Part 3 · Treatment

Beyond movement

Parkinson's affects much more than movement: mood, thinking, sleep, blood pressure, swallowing, the bladder and pain. Press play to travel round the body map, or pick a domain, to see how common each problem is. Then follow the published approach to hallucinations, and what trials found symptom by symptom. This page reports guidelines and trials. It is not advice for any person.

Click a point on the body or a step to choose a domain. The figure is schematic; every bar is a published figure.

Hallucinations and delusions: the published approach

NICE NG71 and the 2019 MDS evidence review set out a sequence: ask and look for causes, leave well-tolerated symptoms alone, reduce the medicines that may have triggered them, and only then add a medicine for psychosis. Impulse-control problems, which are more common on dopamine agonists, are covered in The other medicines.

Schematic. Which medicine is lowered, and by how much, is a specialist decision; the bar levels and meters are illustrative, not doses.

What the trials found, symptom by symptom

A summary of the evidence, with the 2019 MDS ratings where they exist. It is not a treatment plan; any dose mentioned is a trial dose, reported as published.

What drives quality of life

Two studies asked what makes life with Parkinson's better or worse. Both point away from the movement score alone.

Variance explained and rank correlations as published. Bars start at zero.

Reading the evidence

Parkinson's Companion is an educational synthesis of the published literature on Parkinson's disease, made for health-science students, people living with Parkinson's, and the families who care for them.

It is not medical advice. It cannot diagnose, and nothing here should change a treatment without your own clinician. Parkinson's medicines should never be stopped suddenly. Guideline doses are quoted as published. Please check the original sources, which are listed in full in the Sources module.

Part of Medical Companions, animated and cited guides to one disease each. Also there: Alzheimer's Companion, a related guide to the other common neurodegenerative disease, and FMF Companion, on Familial Mediterranean Fever.