Thymectomy removes the thymus, a gland behind the breastbone. Follow the MGTX trial month by month: muscle scores, prednisone doses and remission over 3 and 5 years. Press play, switch the gland view or the surgical approach, and extend the timeline to 5 years.
Published trial and guidance information only. Everything here reports what the MGTX trial, its extension and the consensus guidance published. Whether surgery suits a particular person, and when, is decided by the person with their neurologist and thoracic surgeon.
The gland
Surgery
Show
Masaoka stage
month 0
Anatomy is schematic, not to scale. Filled dots are printed trial values; open dots were read from the published figure and are approximate; lines between them are interpolated.
Who the guidance says it is for
The strongest evidence comes from one randomised trial in a narrow group: adults aged 18 to 65 with generalized, AChR-antibody-positive MG without a thymoma, within 5 years of onset. Outside that group, guidance rests on cohort studies and expert consensus. 381,552
The age-ceiling disagreement
40
Bands show how each source frames age. This is not a recommendation for any person.
Around the operation, thymoma, and the evidence on approach